About Tirzepitide

Tirzepatide is a once-weekly injectable medication used for type 2 diabetes and chronic weight management.

What kind of drug is it?

Tirzepatide is a dual GIP and GLP-1 receptor agonist.

That means it mimics two natural gut hormones:

  • GIP (glucose-dependent insulinotropic polypeptide)
  • GLP-1 (glucagon-like peptide-1)

Most older medications (like semaglutide) only target GLP-1. Tirzepatide activates both receptors, which is why it tends to produce stronger effects on blood sugar control and weight loss.

Brand Names

  • Mounjaro – FDA-approved for type 2 diabetes
  • Zepbound – FDA-approved for chronic weight management

Both contain the same active medication (tirzepatide); they’re just approved for different indications.

What does it do?

Tirzepatide:

  • Increases insulin secretion (when blood sugar is high)
  • Decreases glucagon
  • Slows gastric emptying
  • Reduces appetite
  • Improves insulin sensitivity

Results:

  • Significant A1C reduction (often >2%)
  • Average weight loss of 15–22% in clinical trials at higher doses

How is it taken?

  • Once weekly subcutaneous injection
  • Typical dosing progression:
    • Start: 2.5 mg weekly (starter dose)
    • Increase every 4 weeks
    • Maintenance doses: 5 mg, 7.5 mg, 10 mg, 12.5 mg, or 15 mg

Common Side Effects

  • Nausea
  • Constipation
  • Diarrhea
  • Decreased appetite
  • Reflux

Usually worse during dose escalation.

Serious Warnings

  • Personal or family history of medullary thyroid carcinoma
  • MEN2 syndrome
  • History of pancreatitis (relative caution)
  • Gallbladder disease risk
  • Possible risk of gastroparesis worsening

TIRZEPATIDE INJECTION Special! Monthly Pricing 2.5mg Monthly 5mg $299 Monthly 7.5mg $399 Monthly 10mg $499 Monthly 12.5mg $599 15 mg Monthly $699